Alzheimer Disease

A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Also Known As:

Alzheimer's Disease; Senile Dementia; Early Onset Alzheimer Disease; Late Onset Alzheimer Disease; Primary Senile Degenerative Dementia; Presenile Dementia; Alzheimer Dementia; Alzheimer Disease, Early Onset; Alzheimer Disease, Late Onset; Alzheimer Sclerosis; Alzheimer Syndrome; Alzheimer Type Senile Dementia; Alzheimer's Disease, Focal Onset; Alzheimer-Type Dementia (ATD); Dementia, Presenile; Dementia, Primary Senile Degenerative; Familial Alzheimer Disease (FAD); Focal Onset Alzheimer's Disease; Senile Dementia, Acute Confusional; Alzheimer Dementias; Alzheimer Disease, Familial (FAD); Alzheimer Diseases; Alzheimer Type Dementia; Alzheimer Type Dementia (ATD); Alzheimers Diseases; Dementia, Alzheimer; Dementia, Alzheimer-Type (ATD); Familial Alzheimer Diseases (FAD); Sclerosis, Alzheimer; Acute Confusional Senile Dementia; Alzheimer's Diseases; Dementia, Alzheimer Type; Dementia, Senile; Presenile Alzheimer Dementia; Senile Dementia, Alzheimer Type

Nervous System Diseases: 14178
- Neurodegenerative Diseases: 42472
  - Tauopathies: 2793
    - Alzheimer Disease: 91974
- Central Nervous System Diseases: 4213
  - Brain Diseases: 15694
    - Dementia: 38184
      - Alzheimer Disease: 91974
Mental Disorders: 24177
- Neurocognitive Disorders: 1448
  - Dementia: 38184
    - Alzheimer Disease: 91974

O B McManus Selected Research

O B McManus Research Topics

Disease

Drug/Important Bio-Agent (IBA)